Chemical name
Trimethylol aminomethane (2-amino-2-hydroxymethyl-1, 3-propylene glycol)
CAS number 77-86-1
Common synonyms
TRIS, TRIS, Trizma™, TRIS AMINO™, Tris base, TRIS, trimethylol methylamine
Preparation of buffers for biochemical and molecular biology experiments; Pharmaceutical intermediates; For the preparation of surfactant and vulcanization accelerator; Preparation of water solubility containing Tris structural units; Polymer as paint dispersant; Preparation of indoor formaldehyde adsorption materials, etc.
○ Manufactured according to ISO 9001:2015, with strict process control and monitoring
○ Meet the requirements of IPEC cGMP on pharmaceutical excipients
○ The world's only chemical synthesis process, more than 70 years of production experience
○ Fully traceable supply chain with complete control over basic raw materials
○ Proven safe for use in commercial diagnostic kits, biological macromolecules and chemical drugs
○ Nitrosamine content control level ≤50ppb, fully support medicinal and cosmetic use.
• United States Pharmacopeia - National Prescribing Form (USP-NF)
• European Pharmacopoeia (EP)
• Japan Medical Code (JPC)
• Chinese Pharmacopoeia (Chinese Pharmacopoeia)
典型特性*
| 纯度 | ≥99.9% |
| 分子量 | 121.14 |
| 熔点 | 168-172°C |
| pKa@20℃ | 8.3 |
| pKa@37℃ | 7.8 |
| pKa/℃ | -0.03 |
| pH值，0.1M的水溶液（20℃） | 10.4 |
| △pH /10X稀释 | -0.05到-0.10 |
*The values shown are typical attributes and should not be considered product specifications. Test methods are available upon request.
典型特性*
| 纯度 | ≥99.3%，或≥99.8%（ACS级别） |
| 分子量 | 121.14 |
| 熔点 | 168-172℃ |
| pKa@20℃ | 8.3 |
| pKa@37℃ | 7.8 |
| pKa/℃ | 0.03 |
| pH值为0.1M的水溶液（20℃） | 10.4 |
| △pH/10X稀释 | -0.05到-0.10 |
*The values shown are typical attributes and should not be considered product specifications. Test methods are available upon request.
典型特性*
| 纯度 | ≥99.0% |
| 分子量 | 121.14 |
| 熔点 | 168-172℃ |
| pKa@20℃ | 8.3 |
| pKa@37℃ | 7.8 |
| pKa/℃ | 0.03 |
| pH值为0.1M的水溶液（20℃） | 10.4 |
| △pH/10X稀释 | -0.05到-0.10 |
*The values shown are typical attributes and should not be considered product specifications. Test methods are available upon request.
TRIS AMINO Hydrochloride (CAS No. 1185-53-1) is specially formulated for the formulation of TRIS-HCL buffers, effectively avoiding the use of hazardous chemicals and controlled chemicals hydrochloric acid.
典型特性*
| 纯度（标准级） | 99.0% |
| 纯度（生物制药级别） | 99.5% |
| 重金属总量 | <5ppm |
| 分子量 | 157.6 |
| 熔点 | 150.0——153.0℃ |
| pH值（1.0M水溶液） | 3.7-4.7 |
| pKa@20℃ | 8.0——8.4 |
The biopharmaceutical grade has the most stringent clearance standards on the market, with additional testing for DNase, RNase, proteases, molds/yeasts, endotoxins, bio-loaded items, and the lowest metal impurity levels on the market.
Chemical reaction guarantee Supply capability Guarantee your confidence guarantee
Angus is the world's only fully synthetic producer of TRIS AMINO™ (aminotriol) buffers. Our products meet regulatory requirements around the world and are therefore widely used in the global pharmaceutical and biotechnology sectors. With more than 50 years of experience in the production of triamine, we will continue to provide the booming global market with TRIS AMINO™ products that are even more in line with our customers' requirements, ensuring the best functionality and compliance.
Bailu Bio is a subsidiary of Zhongyuan Bio
Cytiva Guangdong, Guangxi, Hainan exclusive agent
RAININ Guangdong Province level agent
Thermo PA product line national exclusive agent
Angus South China agent
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